Doxepin
Ụdị okwu:3- (10,11-DIHYDRO-5H-DIBENZO[A,D] CYCLOHEPTEN-5-YLIDENE) -N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE; AMITRIPTYLINEHYDROCHLORIDE98+%; AMITRIPTYLINEHYDROCLORIDESOLUTION; 3- (10,11-DIHYDRO-5H-DIBENZO[A,D][7]ANNULEN-5-YLIDENE)-N, N-DIMETHYL-1-PROPANAMINEHYDROCHLORIDE
Nọmba CAS:1668-19-5
Ụdị molekụla: C20H24ClN
Ibu Molecular:313.86
EINECS Mba:208-964-6
Nhazi
Ngwa:Pharmaceuticals, intermediates, APIs, custom synthesis, chemicals
Nke kachasị:Onye na-ere ahịa kacha mma, ogo dị elu, ọnụ ahịa asọmpi, nnyefe ngwa ngwa, nzaghachi ngwa ngwa
Na-eji:Antidepressant, ọdabara dị iche iche mgbaàmà ịda mbà n'obi nke ịda mbà n'obi na organic psychosis
Ụdị emetụtara:Ndị na-egbochi BiogenicAmineTransport; Nchọpụta BiogenicAmineTransportInhibitorsObesity Nnyocha; Neurotransmission; Neurotransmission (oke ibu); Neurotransmitters; Adrenoceptor; Amines; Ndị etiti&FineChemical; Ọgwụ ọgwụ
| Ebe mgbaze | 196-197°C |
| ebe mgbari | 11 Celsius C |
| Njupụta | 1.3134 (atụmatụ siri ike) |
| Ntụgharị ntụgharị | 1.5490 (atụmatụ) |
| Solubility | H2O; soluble |
| Ụdị | ntụ ntụ |
| pKa | 9.4 (na 25 ℃) |
| PH | 4.5 ~ 6.0 (10g/l, 25 ℃) |
| Agba | na-acha ọcha na-acha ọcha |
| Mmiri solubility | Ihe fọrọ nke nta ka ọ bụrụ nghọta |
| Koodu udi egwu | 23/24/25-36/37/38-42/43-63-39/23/24/25-11-50/53-36-22 |
| Nkwupụta nchekwa | 22-26-36/37/39-45-36/37-16-61-60-7 |
| Ụgbọ njem ngwa ahịa dị ize ndụ No | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | HO9450000 |
| Ọkwa ihe egwu | 6.1 (b) |
| Ngalaba nkwakọ ngwaahịa | III |
| Koodu HS | 29214990 |
| Nkọwa pụrụ iche dị ka ihe ndị ahịa chọrọ | |
| Ọdịdị | crystalline ọcha ma ọ bụ ọcha, ọ fọrọ nke nta ka ọ bụrụ ntụ ntụ ọcha |
| Ọnwụ na ihicha | 0.5% kacha |
| Ebe mgbaze | 195-199 ℃ |
| Ihe fọdụrụ na mgbanye | 0.1 max |
| Ịdị ọcha (HPLC) | 98.0-102.0% (na ihicha ndabere) |
| Ụkpụrụ Ogo | Mbipụta USP36 |
Akpachara anya maka njikwa adịghị mma:
Ijikwa na ebe ikuku na-ekuku nke ọma. Yiri uwe nchebe kwesịrị ekwesị. Zere kọntaktị na akpụkpọ ahụ na anya. Zere nhazi nke uzuzu na ikuku ikuku. Jiri ngwa ndị na-adịghị ekpo ọkụ. Gbochie ọkụ na-akpata site na uzuoku mwepu electrostatic.
Ọnọdụ maka nchekwa nchekwa, gụnyere enweghị ndakọrịta ọ bụla:
Debe akpa ahụ nke ọma n'ebe kpọrọ nkụ ma nwee ikuku nke ọma. Ọnọdụ nchekwa akwadoro: 2 - 8 deg C. Debe ebe akọrọ. Amitriptyline hydrochloride.
Jingye nwere 86 set nke reactors na mkpokọta, nke olu nke enamel reactor bụ 69, site na 50 ruo 3000L. Ọnụ ọgụgụ nke igwe anaghị agba nchara bụ 18, site na 50 ruo 3000L. QC nwere ọtụtụ narị ụdị ngwa nyocha niile. Ọ nwere ike izute mmepụta azụmahịa na nyocha zuru oke nke ngwaahịa ahụ. Ngwaahịa a bụ ngwaahịa ntụpọ dị elu ma enwere ike ibunye ya dịka mkpa ndị ahịa siri dị.
Jingye Pharmaceutical management na mmepụta ihe na-akwadosi ike na GMP chọrọ, nke na-enyere Jingye Pharmaceutical mbupụ ngwaahịa ya na Europe, America na South na East Asia. Site na ụlọ ọrụ mmepụta ihe nke ọgbara ọhụrụ, ngwá ọrụ nyocha dị elu na usoro EHS ụda, Jingye Pharmaceutical ejirila akwụkwọ ikike ISO9001, ISO14001 na GB / T28001 kwadoro, ma ugbu a ọ na-aga n'ihu na onye ọkachamara GMP Pharmaceutical Manufacturer.
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